1998—2017年天津市滨海新区塘沽地区儿童青少年死亡原因与减寿分析

目的 了解天津市滨海新区塘沽地区5～19岁儿童青少年的主要死亡原因,为政府等相关部门制定干预措施及政策提供可靠依据。方法 按照国际疾病分类法(ICD-9 和ICD-10)统一编码。用粗死亡率、标化死亡率、死因构成比、潜在减寿年数(PYLL)、潜在减寿率(PYLLR)、标化减寿年数(SPYLL)和标化减寿率(SPYLLR)等健康测量指标对天津市滨海新区塘沽地区20年间的死亡报表进行分析。采用Excel 2017、SPSS 20.0 软件进行统计分析,死亡率的比较采用χ2检验。结果 天津市滨海新区塘沽儿童青少年死亡率为39.02/10万,标化死亡率为5.63/10 万,男性死亡率为27.6/10 万,女性死亡率为18.4/10万,男性高于女性,差异有统计学意义(χ2 =2.87,P<0.05)。损伤中毒(17.33/10万)和肿瘤(9.13/10 万)是危害儿童青少年最主要的死因,占全死因死亡的67.8%。儿童青少年全死因PYLL 为15175.5人年,SPYLL 为8497.37 人年,潜在减寿率 为11.8‰,标化潜在减寿率 为29.5‰。结论 损伤中毒、肿瘤是天津市滨海新区塘沽地区5～19 岁儿童青少年的主要死因,要采取行之有效的干预措施减少死亡,降低疾病负担和寿命损失,促进儿童青少年的身心健康。     

Evaluation of mortality risk factors in diabetic foot infections

Identifying risk factors for mortality is crucial in the management of diabetic foot syndrome. We aimed to evaluate risk factors for mortality in patients with diabetic foot infection (DFI). A retrospective chart review was conducted on 401 patients from 2010 through 2019. Our primary endpoint was in‐hospital mortality. Patients were divided into two groups according to the outcome (survival or death). Clinical data were compared between the two groups statistically. A total of 401 patients were enrolled in the study, 280 (69.8%) of them were male and the mean age was 59.6 ± 11.1 years. The mean follow‐up period was 23.7 ± 22.9 months. In‐hospital mortality rate was 3%. Univariate analysis indicated that ischaemic wound (P = .023), hindfoot infection (P = .038), whole foot infection (P = .010), peripheral arterial disease (P = .024), high leucocyte levels (>12 040 K/μL) (P = .001), high thrombocyte levels (>378 000 K/μL) (P < 0.001), high C‐reactive protein levels (>8.81 mg/dL) (P = .022), and polymicrobial growth in deep tissue culture (P = .041) were significant parameters in predicting mortality. In multivariate analysis, peripheral arterial disease (odds ratio [OR]: 13.430, 95% confidence interval [Cl]: 1.129‐59.692; P = .040), high thrombocyte levels (OR: 1.000, 95% Cl: 1.000‐1.000; P = .022), and polymicrobial growth in deep tissue culture (OR: 7.790, 95% Cl: 1.592‐38.118; P = .011) were independent risk factors for mortality. In conclusion, peripheral arterial disease, high thrombocyte levels, and polymicrobial growth in deep tissue culture were independent risk factors for mortality in DFI.